Update, 10:15 p.m.: Madison Street is cleared and back open, according to police.
The driver who was flown by LifeFlight is in critical but stable condition. The second driver is in stable condition.
Anyone with information about the wreck is asked to contact Investigator Nemeth at 931-320-0414.
Previously:
CLARKSVILLE, TN (CLARKSVILLE NOW) – A vehicle going the wrong way on Madison Street hit another head-on, with serious injuries to both drivers.
At about 6:50 p.m., the vehicles crashed at Denny Road in front of Burger King, according to Clarksville Police spokesman Scott Beaubien.
As of 7:45 p.m., the eastbound lanes of Madison were shut down, and one westbound lane was shut down.
“This is causing major traffic congestion and the Clarksville Police Department is asking the public to avoid the area and find alternate routes,” Beaubien said.
One individual was taken by LifeFlight to Nashville and another driver was being driven to Skyline Hospital.
Investigators with the Fatal Accident Crash Team are en route to the scene.
No further information has been released.